I've been slowly and somewhat reluctantly transitioning to working "in the cloud," i.e. doing everything on the internet. One motivation is travel; another is trying to sync across three computers (desktop at work, big laptop and small laptop at home, with the fried hard drive of the big laptop) and two devices (iPod touch and Nook). On Monday my desktop at work imploded, and I lost everything on the hard drive. Luckily I can reconstruct mostly everything, but it's still not fun trying to catch up. Actually what I miss the most is my to-do list, which I'd kept in the "tasks" section of Outlook, now sadly gone.
So I've uploaded everything (both personal and work files) unto Dropbox which has worked out pretty well. Most of our photos are on Picasa and music on the iPod (mine) or Walkman (his) but I shelled out anyway for more space. I've been using Google Docs for the past couple of years; I really don't like how it formats (or not) so I usually end up writing drafts in Google and reformatting on Word. I still try to back-up all our files to an external hard drive every quarter. Luckily that's not such an onerous task.
I've also designated a USB thumb drive as my official "work" device. It's loaded with portable apps as well as scans of the ID pages of my two passports (official and personal), a PDF of the laptop manual, PDFs of invoices from Dell (in case I ever need to prove ownership), Windows 7 restore files, and other important items.
Of course, I'm assuming I'll have electricity and internet wherever I work - not always a workable assumption.